glutaminase相关论文
Curcumin Synergizes with Cisplatin to Inhibit Colon Cancer through Targeting the MicroRNA-137-Glutam
Objective:Colorectal cancer(CRC)is one of the most lethal and prevalent malignancies world-wide.Currently,surgery,radiot......
Identification of dual inhibitors of glutaminase and glutamate dehydrogenase that disrupt mitochondr
Glutaminase(KGA/isoenzyme GAC)is an emerging and important drug target for cancer.Traditional methods for assaying gluta......
Glutaminase is widely distributed among microorganisms and mammals with important functions. Lit-tle is known regarding ......
Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats followi
AIM: To assess whether portacaval anastomosis (PCA) in rats affects the protein expression and/or activity of glutaminas......
[目的]观察鱼藤酮对神经细胞谷氨酸代谢关键酶表达的影响。[方法]在体外建立星形胶质细胞与PC12细胞共培养鱼藤酮染毒模型,采用RT-......
阜阳市局 £4a 局长——_MINtkMMtgj’#lnH$B——q.M——D收束志不他只邀狲位J则【科校为先导推动地租工作.B为广为戳民U用凶盼引眯B.......
Purification,characterization and antiproliferative activity of L-asparaginase from Aspergillus oryz
Objective:To explore the anti-proliferative activity of purified L-asparaginase from Aspergillus oryzae CCT 3940(A.oryza......
EFFECTS OF L-GLUTAMINE, GLUTAMINASE AND GLUTAMINE SYNTHETASE ON CAP THRESHOLD OF COCHLEAR NERVE OF G
Negative direct current (__DC 300 μA) stimulation was applied to the round window ofthe guinea pig cochlea to exhaust t......
Many cancer types reprogram their metabolism to become addicted to glutamine. One of the critical enzymes in the utiliza......
ALTERATION IN ENTEROCYTE GENE EXPRESSION MAY EXPLAIN STRUCTURAL AND FUNCTIONAL CHANGES FOLLOWING GLU
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
摘要:利用谷氨酰胺酶(EC3.2.1.5)对大豆分离蛋白进行限制性脱酰胺和水解处理,以SDS—PAGEYL排阻色谱分析评价产物的蛋白质降解情况.并制备......
以酱油曲中的谷氨酰胺酶为研究对象,通过蒸氨法测定谷氨酰胺酶酶活力,探究不同温度、pH、NaCl浓度对谷氨酰胺酶酶活力和稳定性的影......
目的:构建大鼠谷氨酰胺酶(GA)反义真核表达载体. 方法:采用分子克隆技术将rGA cDNA反向克隆到真核表达载体pcDNA 3.0中. 结果:Eco ......
为探讨旋毛虫肌幼虫谷氨酰胺酶(TsGLS)在酸性条件下的作用,本研究应用实时荧光定量PCR和免疫荧光技术对不同pH值条件下培养TsGLS的表......
肿瘤细胞利用各种代谢途径以满足增殖的能量和生物合成需求。除葡萄糖外,谷氨酰胺也是肿瘤细胞生长的重要前体物质及能量来源。谷......
为验证谷氨酰胺酶基因glsA2的酶活力,以pET-32a为表达载体构建原核表达重组质粒pET32a-glsA2,转化表达菌株E.coli BL21(DE3)。从异丙......
将含有谷氨酰胺酶的猪肾组织切片固定于聚酯膜和聚碳酸酯膜之间,并与氨电极偶合制成L-谷氨酰胺传感器。线性范围10<sup>-4</sup>~5&......
为筛选获得高活性谷氨酰胺酶豆豉芽孢杆菌菌株,提高谷氨酸的含量,试验通过康维皿弥散法对525株芽孢杆菌进行酶活检测,获得一株产谷......
Biosynthesis is up-regulated in tumors and thus the demand for anabolic intermediates is increased. The metabolic routes......
Aim To study if inhibition of glutaminase has effect on polycystic kidney disease (PKD)development and to further investig......